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Christina Cohen has dominated her world in every possible way to make the most out of life. She is a diligent student and a working girl to take on the world and fulfill her hopes and accomplish her dreams. So, when she fails to secure her grades, Prof. Gordon agrees to give her a passing grade, but there is another challenge which she must accept to ensure she is once again on the path to fulfill her ambition. Gordon becomes the right man to enlighten her about her twisted side because in his able hands, she becomes a hundred different women.
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Icariin is a major bioactive pharmaceutical constituent isolated from Chinese medicine Horny Goat Weed Ying Yang Huo with potent cardiovascular protective functions. Emerging evidence in the past decade has shown that Icariin possesses multiple atheroprotective functions, through multiple mechanisms, including attenuating DNA damage, correcting endothelial dysfunction, inhibiting the proliferation and migration of smooth muscle cells, repressing macrophage-derived foam cell formation and inflammatory responses, as well as preventing platelet activation. All of these protective effects, combined with its lipid-modulatory effects, contribute to the broad atheroprotective effects of Icariin. In this review, we will summarize the anti-atherosclerotic properties of Icariin and highlight future perspectives in developing Icariin as a promising anti-atherosclerotic drug. Cardiovascular diseases CVDs represent one of the leading causes of death in the modern society worldwide Benjamin et al.
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